Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM50455394'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50455394 (CHEMBL4208161) Show SMILES COc1ccc(cc1)C(=O)N1CCc2cc(OC)c(OC3CCCC3)cc2C1 Show InChI InChI=1S/C23H27NO4/c1-26-19-9-7-16(8-10-19)23(25)24-12-11-17-13-21(27-2)22(14-18(17)15-24)28-20-5-3-4-6-20/h7-10,13-14,20H,3-6,11-12,15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 1188-1193 (2018) Article DOI: 10.1016/j.bmcl.2018.02.056 BindingDB Entry DOI: 10.7270/Q2W66PBS
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