Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM50527535'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50527535 (CHEMBL4589927) Show SMILES [H][C@@]12CC=CC[C@]1([H])C(=NN(C1CCN(CC1)c1ncnc3ccccc13)C2=O)c1ccc(OC)c(OC)c1 |r,c:3,9| Show InChI InChI=1S/C29H31N5O3/c1-36-25-12-11-19(17-26(25)37-2)27-21-7-3-4-8-22(21)29(35)34(32-27)20-13-15-33(16-14-20)28-23-9-5-6-10-24(23)30-18-31-28/h3-6,9-12,17-18,20-22H,7-8,13-16H2,1-2H3/t21-,22+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit based				J Med Chem 63: 3485-3507 (2020) Article DOI: 10.1021/acs.jmedchem.9b00985 BindingDB Entry DOI: 10.7270/Q20005JV
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