Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM107778'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM107778 (US8598155, 15) Show SMILES CCc1ccc(cc1)-c1c(cnn1C)-c1nc(C)n2ncnc(N3CCC3)c12 Show InChI InChI=1S/C21H23N7/c1-4-15-6-8-16(9-7-15)19-17(12-23-26(19)3)18-20-21(27-10-5-11-27)22-13-24-28(20)14(2)25-18/h6-9,12-13H,4-5,10-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.517	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximity assay (SPA) modifie...				US Patent US8598155 (2013) BindingDB Entry DOI: 10.7270/Q26T0K8C
					More data for this Ligand-Target Pair