Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM130996'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM130996 (US8829010, 47) Show SMILES CC(C)c1ccc(cc1)-c1c(cnn1C)-c1nn(C)c2ncnc(N3CCC3)c12 Show InChI InChI=1S/C22H25N7/c1-14(2)15-6-8-16(9-7-15)20-17(12-25-27(20)3)19-18-21(28(4)26-19)23-13-24-22(18)29-10-5-11-29/h6-9,12-14H,5,10-11H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description In the present assay, the activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximi...				US Patent US8829010 (2014) BindingDB Entry DOI: 10.7270/Q2PR7TNH
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