Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM204136'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM204136 (8-Chloro-1-(2-chloro-phenyl)-4-methyl-[1,2,4]triaz...) Show SMILES Cc1nc2ccc(Cl)cc2n2c(nnc12)-c1ccccc1Cl Show InChI InChI=1S/C16H10Cl2N4/c1-9-15-20-21-16(11-4-2-3-5-12(11)18)22(15)14-8-10(17)6-7-13(14)19-9/h2-8H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The DNA encoding PDE2A (NM002599) was cloned and the gene was inserted in the baculovirus and the enzyme-protein expressed in SF21-cells. The enzyme ...				US Patent US9540379 (2017) BindingDB Entry DOI: 10.7270/Q2RB72SP
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