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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM372182'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-dependent 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM372182
PNG
(US10239882, Example 29)
Show SMILES COc1ccc(CNc2nc3nc(cc(C4CCOCC4)n3n2)C(F)F)cc1
Show InChI InChI=1S/C19H21F2N5O2/c1-27-14-4-2-12(3-5-14)11-22-18-24-19-23-15(17(20)21)10-16(26(19)25-18)13-6-8-28-9-7-13/h2-5,10,13,17H,6-9,11H2,1H3,(H,22,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



National Taiwan University



Assay Description
An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...

J Med Chem 51: 2795-806 (2008)


BindingDB Entry DOI: 10.7270/Q24J0HFD
More data for this
Ligand-Target Pair