Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50007222'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50007222 (1,3,9,9a-Tetrahydro-imidazo[4,5-b]quinolin-2-one |...) Show SMILES O=c1[nH]c2Cc3ccccc3Nc2[nH]1 Show InChI InChI=1S/C10H9N3O/c14-10-12-8-5-6-3-1-2-4-7(6)11-9(8)13-10/h1-4,11H,5H2,(H2,12,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of cGMP hydrolysis by human platelet phosphodiesterase				J Med Chem 34: 2906-16 (1991) BindingDB Entry DOI: 10.7270/Q20P0Z03
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