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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50162702'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-dependent 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50162702
PNG
(CHEMBL3793675)
Show SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)C(=C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)C[C@@H](O)[C@@H](OC(=O)\C=C\c1ccc(O)cc1)C2(C)C |r,t:9|
Show InChI InChI=1S/C39H52O6/c1-23-16-19-39(34(43)44)21-20-37(6)27(32(39)24(23)2)13-14-30-36(5)22-28(41)33(35(3,4)29(36)17-18-38(30,37)7)45-31(42)15-10-25-8-11-26(40)12-9-25/h8-13,15,24,28-30,32-33,40-41H,1,14,16-22H2,2-7H3,(H,43,44)/b15-10+/t24-,28+,29-,30+,32-,33+,36-,37+,38+,39-/m0/s1
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Similars
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Sun Yat-Sen University

Curated by ChEMBL


Assay Description
Inhibition of PDE2A3 catalytic domain (222 to 904 residues) (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintilla...

Eur J Med Chem 114: 134-40 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.002
BindingDB Entry DOI: 10.7270/Q2765H8J
More data for this
Ligand-Target Pair