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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50258302'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-dependent 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50258302
PNG
(CHEMBL4086618)
Show SMILES CCC(NC(=O)c1cnn2c(C)cc(C)nc12)c1ccc(OC)cc1
Show InChI InChI=1S/C19H22N4O2/c1-5-17(14-6-8-15(25-4)9-7-14)22-19(24)16-11-20-23-13(3)10-12(2)21-18(16)23/h6-11,17H,5H2,1-4H3,(H,22,24)
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.

Curated by ChEMBL


Assay Description
Inhibition of PDE2A (unknown origin)

J Med Chem 60: 7658-7676 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00709
BindingDB Entry DOI: 10.7270/Q2TT4TD5
More data for this
Ligand-Target Pair