Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50258933'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50258933 (CHEMBL4068452) Show SMILES CC(C)(O)C(NC(=O)N1CC(=O)Nc2cccnc12)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C19H19F3N4O4/c1-18(2,29)15(11-5-7-12(8-6-11)30-19(20,21)22)25-17(28)26-10-14(27)24-13-4-3-9-23-16(13)26/h3-9,15,29H,10H2,1-2H3,(H,24,27)(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Activity at Histamine H1 receptor using functional H1 receptor assay on guinea pig ileum				Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50258933 (CHEMBL4068452) Show SMILES CC(C)(O)C(NC(=O)N1CC(=O)Nc2cccnc12)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C19H19F3N4O4/c1-18(2,29)15(11-5-7-12(8-6-11)30-19(20,21)22)25-17(28)26-10-14(27)24-13-4-3-9-23-16(13)26/h3-9,15,29H,10H2,1-2H3,(H,24,27)(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate by scintillation proximity assay				J Med Chem 60: 7677-7702 (2017) Article DOI: 10.1021/acs.jmedchem.7b00807 BindingDB Entry DOI: 10.7270/Q2P271JR
					More data for this Ligand-Target Pair