Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50425126'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50425126 (CHEMBL2313231) Show SMILES Cc1nc2ccc(cc2n2c(nnc12)-c1ccccc1Cl)C(=O)NCc1ccccn1 Show InChI InChI=1S/C23H17ClN6O/c1-14-21-28-29-22(17-7-2-3-8-18(17)24)30(21)20-12-15(9-10-19(20)27-14)23(31)26-13-16-6-4-5-11-25-16/h2-12H,13H2,1H3,(H,26,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE2A expressed in Sf9 cells by scintillation proximity assay				Bioorg Med Chem Lett 23: 785-90 (2013) Article DOI: 10.1016/j.bmcl.2012.11.077 BindingDB Entry DOI: 10.7270/Q2C82BMR
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