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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50540316'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-dependent 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50540316
PNG
(CHEMBL4635049)
Show SMILES CCc1ccc(cc1)-c1c(cnn1C)-c1nn(C)c2ncnc(N3CC(O)C3)c12
Show InChI InChI=1S/C21H23N7O/c1-4-13-5-7-14(8-6-13)19-16(9-24-26(19)2)18-17-20(27(3)25-18)22-12-23-21(17)28-10-15(29)11-28/h5-9,12,15,29H,4,10-11H2,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE2 (unknown origin)

J Med Chem 63: 6387-6406 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01840
BindingDB Entry DOI: 10.7270/Q2X06BK1
More data for this
Ligand-Target Pair