Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent protein kinase' and Ligand = 'BDBM340925'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase ()	BDBM340925 (3-(6-(3-chloro-4-(2,2,2- trifluorethyl)benzyloxy)n...) Show SMILES CC(C)n1nc(-c2ccc3cc(OCc4ccc(CC(F)(F)F)c(Cl)c4)ccc3c2)c2c(N)ncnc12 Show InChI InChI=1S/C27H23ClF3N5O/c1-15(2)36-26-23(25(32)33-14-34-26)24(35-36)19-6-5-18-11-21(8-7-17(18)10-19)37-13-16-3-4-20(22(28)9-16)12-27(29,30)31/h3-11,14-15H,12-13H2,1-2H3,(H2,32,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...				Citation and Details BindingDB Entry DOI: 10.7270/Q2K077GQ
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