Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-dependent protein kinase' and Ligand = 'BDBM50168204'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50168204 (4-[2-(4-Fluoro-phenyl)-5-(1-propyl-piperidin-4-yl)...) Show SMILES CCCN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C23H26FN3/c1-2-13-27-14-9-18(10-15-27)22-16-21(17-7-11-25-12-8-17)23(26-22)19-3-5-20(24)6-4-19/h3-8,11-12,16,18,26H,2,9-10,13-15H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of Eimeria tenella cGMP-dependent protein kinase				Bioorg Med Chem Lett 15: 3296-301 (2005) Article DOI: 10.1016/j.bmcl.2005.04.060 BindingDB Entry DOI: 10.7270/Q24M9421
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50168204 (4-[2-(4-Fluoro-phenyl)-5-(1-propyl-piperidin-4-yl)...) Show SMILES CCCN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C23H26FN3/c1-2-13-27-14-9-18(10-15-27)22-16-21(17-7-11-25-12-8-17)23(26-22)19-3-5-20(24)6-4-19/h3-8,11-12,16,18,26H,2,9-10,13-15H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella				Bioorg Med Chem Lett 15: 4570-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.096 BindingDB Entry DOI: 10.7270/Q2416WM9
					More data for this Ligand-Target Pair