Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-dependent protein kinase' and Ligand = 'BDBM50345708'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase ()	BDBM50345708 (2-(4-amino-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3...) Show SMILES NC(=O)Cn1nc(Cc2cccc3ccccc23)c2c(N)ncnc12 Show InChI InChI=1S/C18H16N6O/c19-15(25)9-24-18-16(17(20)21-10-22-18)14(23-24)8-12-6-3-5-11-4-1-2-7-13(11)12/h1-7,10H,8-9H2,(H2,19,25)(H2,20,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Kinase phosphorylation reactions were performed in a buffered medium containing 20 mM HEPES pH 7.5 (KOH), 0.1% BSA, 10 mM MgCl2, 1 mM EGTA (pH 7.2), ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2K077GQ
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase ()	BDBM50345708 (2-(4-amino-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3...) Show SMILES NC(=O)Cn1nc(Cc2cccc3ccccc23)c2c(N)ncnc12 Show InChI InChI=1S/C18H16N6O/c19-15(25)9-24-18-16(17(20)21-10-22-18)14(23-24)8-12-6-3-5-11-4-1-2-7-13(11)12/h1-7,10H,8-9H2,(H2,19,25)(H2,20,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...				Citation and Details BindingDB Entry DOI: 10.7270/Q2K077GQ
					More data for this Ligand-Target Pair