Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B' and Ligand = 'BDBM50024406'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50024406 (5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...) Show SMILES Cc1[nH]c(=O)c(cc1-c1ccc(cc1)-n1ccnc1)C#N Show InChI InChI=1S/C16H12N4O/c1-11-15(8-13(9-17)16(21)19-11)12-2-4-14(5-3-12)20-7-6-18-10-20/h2-8,10H,1H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of cGMP phosphodiesterase PDE 2 from guinea pig, range 27-41				J Med Chem 30: 1023-9 (1987) BindingDB Entry DOI: 10.7270/Q2862FF4
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