Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B' and Ligand = 'BDBM50045010'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50045010 (2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[...) Show SMILES COc1cc(ccc1-c1nc2cnccc2[nH]1)[S+](C)[O-] Show InChI InChI=1S/C14H13N3O2S/c1-19-13-7-9(20(2)18)3-4-10(13)14-16-11-5-6-15-8-12(11)17-14/h3-8H,1-2H3,(H,16,17)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents		n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration of compound required for 50% inhibition of type III cAMP phosphodiesterase from dog ventricles, activity expressed as pIC50				Citation and Details BindingDB Entry DOI: 10.7270/Q26D5W5H
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50045010 (2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[...) Show SMILES COc1cc(ccc1-c1nc2cnccc2[nH]1)[S+](C)[O-] Show InChI InChI=1S/C14H13N3O2S/c1-19-13-7-9(20(2)18)3-4-10(13)14-16-11-5-6-15-8-12(11)17-14/h3-8H,1-2H3,(H,16,17)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of PDE 3 (phosphodiesterase III) from guinea pig ventricle				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
					More data for this Ligand-Target Pair