Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B' and Ligand = 'BDBM50227407'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50227407 (CHEMBL28756) Show SMILES CCOc1cc2c(C)nc(O)c(CC)c2cc1OC Show InChI InChI=1S/C15H19NO3/c1-5-10-12-8-13(18-4)14(19-6-2)7-11(12)9(3)16-15(10)17/h7-8H,5-6H2,1-4H3,(H,16,17)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ortho Pharmaceutical Corporation Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase fraction III in anesthetized open chest dogs				J Med Chem 31: 1363-8 (1988) BindingDB Entry DOI: 10.7270/Q2SX6GFZ
					More data for this Ligand-Target Pair