Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B' and Ligand = 'BDBM50228381'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50228381 (CHEMBL124869) Show SMILES CC1CC(=O)NN=C1c1ccc2OCCN(c2c1)S(C)(=O)=O |c:6| Show InChI InChI=1S/C14H17N3O4S/c1-9-7-13(18)15-16-14(9)10-3-4-12-11(8-10)17(5-6-21-12)22(2,19)20/h3-4,8-9H,5-7H2,1-2H3,(H,15,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of cardiac phosphodiesterase-3 isolated from canine heart.				J Med Chem 33: 380-6 (1990) BindingDB Entry DOI: 10.7270/Q241708F
					More data for this Ligand-Target Pair