Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human)) | BDBM50246908 (CHEMBL4093768) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiesi Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Inhibition of human recombinant PDE3A expressed insect sf9 cells by radiometric assay | J Med Chem 60: 10026-10046 (2017) Article DOI: 10.1021/acs.jmedchem.7b01044 BindingDB Entry DOI: 10.7270/Q25H7JN4 | |||||||||||
More data for this Ligand-Target Pair |