Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B' and Ligand = 'BDBM50128265'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50128265 (CHEMBL3629000) Show SMILES Cn1ncc(c1-c1ccc(OCc2cc(-n3cc(CCF)nn3)c3ccccc3n2)cc1)-c1ccncc1 Show InChI InChI=1S/C29H24FN7O/c1-36-29(26(17-32-36)20-11-14-31-15-12-20)21-6-8-24(9-7-21)38-19-23-16-28(25-4-2-3-5-27(25)33-23)37-18-22(10-13-30)34-35-37/h2-9,11-12,14-18H,10,13,19H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE3B assessed as reduction of [3H]-cAMP hydrolysis preincubated for 5 mins followed by [3H]-cAMP addition measured a...				J Med Chem 58: 8584-600 (2015) Article DOI: 10.1021/acs.jmedchem.5b01205 BindingDB Entry DOI: 10.7270/Q2C53NPQ
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