Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B' and Ligand = 'BDBM50128275'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50128275 (CHEMBL3628724) Show SMILES Cn1cc(c(n1)-c1ccc(OCc2ccc3cc(F)ccc3n2)cc1)-c1ccncc1 Show InChI InChI=1S/C25H19FN4O/c1-30-15-23(17-10-12-27-13-11-17)25(29-30)18-3-7-22(8-4-18)31-16-21-6-2-19-14-20(26)5-9-24(19)28-21/h2-15H,16H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE3B assessed as reduction of [3H]-cAMP hydrolysis preincubated for 5 mins followed by [3H]-cAMP addition measured a...				J Med Chem 58: 8584-600 (2015) Article DOI: 10.1021/acs.jmedchem.5b01205 BindingDB Entry DOI: 10.7270/Q2C53NPQ
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