Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM258394'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM258394 (US9505786, 32) Show SMILES CCCc1nc(nc2NC(=O)C(C)(C)c12)-c1nn(Cc2ccccc2F)c2ncccc12 Show InChI InChI=1S/C24H23FN6O/c1-4-8-17-18-20(29-23(32)24(18,2)3)28-21(27-17)19-15-10-7-12-26-22(15)31(30-19)13-14-9-5-6-11-16(14)25/h5-7,9-12H,4,8,13H2,1-3H3,(H,27,28,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	7.5	25
BAYER PHARMA AKTIENGESELLSCHAFT; BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...				US Patent US9505786 (2016) BindingDB Entry DOI: 10.7270/Q2WS8S6V
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