Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM312952'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM312952 (7,7-Dimethyl-3-[6-methyl-1-(2,3,6-trifluorobenzyl)...) Show SMILES Cc1ccc2c(nn(Cc3c(F)ccc(F)c3F)c2n1)-c1nnc2c(NC(=O)C2(C)C)n1 Show InChI InChI=1S/C21H16F3N7O/c1-9-4-5-10-15(17-26-18-16(28-29-17)21(2,3)20(32)27-18)30-31(19(10)25-9)8-11-12(22)6-7-13(23)14(11)24/h4-7H,8H2,1-3H3,(H,26,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...				US Patent US9605008 (2017) BindingDB Entry DOI: 10.7270/Q2DZ0BC2
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