Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM312963'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM312963 (3′-[1-(2,3-Difluorobenzyl)-6-methyl-1H-pyraz...) Show SMILES Cc1ccc2c(nn(Cc3cccc(F)c3F)c2n1)-c1nnc2c(NC(=O)C22CC2)n1 Show InChI InChI=1S/C21H15F2N7O/c1-10-5-6-12-15(17-25-18-16(27-28-17)21(7-8-21)20(31)26-18)29-30(19(12)24-10)9-11-3-2-4-13(22)14(11)23/h2-6H,7-9H2,1H3,(H,25,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...				US Patent US9605008 (2017) BindingDB Entry DOI: 10.7270/Q2DZ0BC2
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