Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50017100 (4-(3-Butoxy-phenyl)-pyrrolidin-2-one | CHEMBL32226) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Neurochimie du CNRS Curated by ChEMBL | Assay Description Inhibition of cGMP-PDE phosphodiesterase from bovine aorta using 1 uM cGMP | J Med Chem 32: 1450-7 (1989) BindingDB Entry DOI: 10.7270/Q2DN441H | |||||||||||
More data for this Ligand-Target Pair |