Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50066446'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50066446 (4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-1-chloro-p...) Show SMILES Clc1nnc(NCc2ccc3OCOc3c2)c2cc(ccc12)C#N Show InChI InChI=1S/C17H11ClN4O2/c18-16-12-3-1-10(7-19)5-13(12)17(22-21-16)20-8-11-2-4-14-15(6-11)24-9-23-14/h1-6H,8-9H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from porcine platelets				J Med Chem 41: 3367-72 (1998) Article DOI: 10.1021/jm970815r BindingDB Entry DOI: 10.7270/Q2MS3RXG
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