Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50178872'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50178872 (2-(5-methyl-thiophen-2-yl)-quinoline-4-carboxylic ...) Show SMILES Cc1ccc(s1)-c1cc(C(=O)Nc2ccc(cc2)S(N)(=O)=O)c2ccccc2n1 Show InChI InChI=1S/C21H17N3O3S2/c1-13-6-11-20(28-13)19-12-17(16-4-2-3-5-18(16)24-19)21(25)23-14-7-9-15(10-8-14)29(22,26)27/h2-12H,1H3,(H,23,25)(H2,22,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 16: 1371-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.046 BindingDB Entry DOI: 10.7270/Q2B56J9C
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