Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50178875'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50178875 (4-[5-(4-Oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno...) Show SMILES OC(=O)c1ccc(cc1)-c1ccc(o1)-c1nc2sc3CCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C21H16N2O4S/c24-19-17-13-3-1-2-4-16(13)28-20(17)23-18(22-19)15-10-9-14(27-15)11-5-7-12(8-6-11)21(25)26/h5-10H,1-4H2,(H,25,26)(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 16: 1371-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.046 BindingDB Entry DOI: 10.7270/Q2B56J9C
					More data for this Ligand-Target Pair