Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50256771'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50256771 (CHEMBL474226 | ethyl 2-(4-(4-(dimethylamino)piperi...) Show SMILES CCOC(=O)c1sc(Nc2nc(cc(n2)N2CCCC(CO)C2)N2CCC(CC2)N(C)C)nc1C Show InChI InChI=1S/C24H37N7O3S/c1-5-34-22(33)21-16(2)25-24(35-21)28-23-26-19(30-11-8-18(9-12-30)29(3)4)13-20(27-23)31-10-6-7-17(14-31)15-32/h13,17-18,32H,5-12,14-15H2,1-4H3,(H,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 19: 1935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.060 BindingDB Entry DOI: 10.7270/Q2TM7B02
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