Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM69375'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM69375 (2-(3-pyridinyl)-N-(thiophen-2-ylmethyl)-4-quinazol...) Show SMILES C(Nc1nc(nc2ccccc12)-c1cccnc1)c1cccs1 Show InChI InChI=1S/C18H14N4S/c1-2-8-16-15(7-1)18(20-12-14-6-4-10-23-14)22-17(21-16)13-5-3-9-19-11-13/h1-11H,12H2,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Biofor Inc. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 from human platelets				J Med Chem 38: 3547-57 (1995) BindingDB Entry DOI: 10.7270/Q2F190CB
					More data for this Ligand-Target Pair