Found 8 hits Enz. Inhib. hit(s) with Target = 'eIF-2-alpha kinase GCN2' and Ligand = 'BDBM614965' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 26.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 26.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this Ligand-Target Pair | |