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Target
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Compile Data Set for Download or QSAR
Found
4
hits Enz. Inhib. hit(s) with Target = 'eIF-2-alpha kinase GCN2' and Ligand = 'BDBM614995'
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
BDBM614995
(US20230271939, Example 33)
Show SMILES
COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]nc(C)c3c2)c1F
Show InChI
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
US Patent
0.300
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
Celgene Quanticel Research, Inc.
US Patent
US Patent
US10174003 (2019)
BindingDB Entry DOI:
10.7270/Q2Q244CX
More data for this
Ligand-Target Pair
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
BDBM614995
(US20230271939, Example 33)
Show SMILES
COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]nc(C)c3c2)c1F
Show InChI
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
US Patent
1.30
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
Celgene Quanticel Research, Inc.
US Patent
US Patent
US10174003 (2019)
BindingDB Entry DOI:
10.7270/Q2Q244CX
More data for this
Ligand-Target Pair
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
BDBM614995
(US20230271939, Example 33)
Show SMILES
COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]nc(C)c3c2)c1F
Show InChI
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
US Patent
n/a
n/a
4.20
n/a
n/a
n/a
n/a
n/a
n/a
Celgene Quanticel Research, Inc.
US Patent
US Patent
US10174003 (2019)
BindingDB Entry DOI:
10.7270/Q2Q244CX
More data for this
Ligand-Target Pair
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
BDBM614995
(US20230271939, Example 33)
Show SMILES
COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]nc(C)c3c2)c1F
Show InChI
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
US Patent
n/a
n/a
21.7
n/a
n/a
n/a
n/a
n/a
n/a
Celgene Quanticel Research, Inc.
US Patent
US Patent
US10174003 (2019)
BindingDB Entry DOI:
10.7270/Q2Q244CX
More data for this
Ligand-Target Pair
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