Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'fMet-Leu-Phe receptor' and Ligand = 'BDBM50295519'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50295519 (CHEMBL554291 | N-(3,4-Dimethoxyphenyl)-2-[5-(3-met...) Show SMILES COc1cccc(Cc2cc(C)nn(CC(=O)Nc3ccc(OC)c(OC)c3)c2=O)c1 Show InChI InChI=1S/C23H25N3O5/c1-15-10-17(11-16-6-5-7-19(12-16)29-2)23(28)26(25-15)14-22(27)24-18-8-9-20(30-3)21(13-18)31-4/h5-10,12-13H,11,14H2,1-4H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Agonist activity at FPR1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assay				J Med Chem 52: 5044-57 (2010) Article DOI: 10.1021/jm900592h BindingDB Entry DOI: 10.7270/Q2WS8T85
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50295519 (CHEMBL554291 | N-(3,4-Dimethoxyphenyl)-2-[5-(3-met...) Show SMILES COc1cccc(Cc2cc(C)nn(CC(=O)Nc3ccc(OC)c(OC)c3)c2=O)c1 Show InChI InChI=1S/C23H25N3O5/c1-15-10-17(11-16-6-5-7-19(12-16)29-2)23(28)26(25-15)14-22(27)24-18-8-9-20(30-3)21(13-18)31-4/h5-10,12-13H,11,14H2,1-4H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Agonist activity at FPR1 in human neutrophiles by chemotaxis assay				J Med Chem 52: 5044-57 (2010) Article DOI: 10.1021/jm900592h BindingDB Entry DOI: 10.7270/Q2WS8T85
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50295519 (CHEMBL554291 | N-(3,4-Dimethoxyphenyl)-2-[5-(3-met...) Show SMILES COc1cccc(Cc2cc(C)nn(CC(=O)Nc3ccc(OC)c(OC)c3)c2=O)c1 Show InChI InChI=1S/C23H25N3O5/c1-15-10-17(11-16-6-5-7-19(12-16)29-2)23(28)26(25-15)14-22(27)24-18-8-9-20(30-3)21(13-18)31-4/h5-10,12-13H,11,14H2,1-4H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Agonist activity at FPR1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assay				J Med Chem 52: 5044-57 (2010) Article DOI: 10.1021/jm900592h BindingDB Entry DOI: 10.7270/Q2WS8T85
					More data for this Ligand-Target Pair