Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'hek293 luciferase' and Ligand = 'BDBM50502733'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
hek293 luciferase (Human immunodeficiency virus type 1 group M subtyp...)	BDBM50502733 (CHEMBL4446699 | US11479539, Compound 80) Show SMILES CO[C@]1(CC(C)(C)C(=O)C(=C1)C#N)c1ncc(F)cc1-c1ccns1 |r,c:9| Show InChI InChI=1S/C18H16FN3O2S/c1-17(2)10-18(24-3,7-11(8-20)16(17)23)15-13(6-12(19)9-21-15)14-4-5-22-25-14/h4-7,9H,10H2,1-3H3/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA					Assay Description Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...				Citation and Details BindingDB Entry DOI: 10.7270/Q2GQ720P
					More data for this Ligand-Target Pair