Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'm7GpppX diphosphatase' and Ligand = 'BDBM50237212'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
m7GpppX diphosphatase (Homo sapiens (Human))	BDBM50237212 (CHEMBL4100442) Show SMILES Cc1cc(OCC2CCN(Cc3ccccc3F)CC2)c2c(N)nc(N)nc2c1 Show InChI InChI=1S/C22H26FN5O/c1-14-10-18-20(21(24)27-22(25)26-18)19(11-14)29-13-15-6-8-28(9-7-15)12-16-4-2-3-5-17(16)23/h2-5,10-11,15H,6-9,12-13H2,1H3,(H4,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DcpS assessed as increase in SMN2 promoter activity				J Med Chem 60: 3094-3108 (2017) Article DOI: 10.1021/acs.jmedchem.7b00124 BindingDB Entry DOI: 10.7270/Q2251MG2
					More data for this Ligand-Target Pair