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Found 1 hit Enz. Inhib. hit(s) with Target = 'rRNA adenine N-6-methyltransferase' and Ligand = 'BDBM50292290'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
rRNA adenine N-6-methyltransferase


(Staphylococcus aureus (strain N315))		BDBM50292290
PNG
(CHEMBL4159457)
Show SMILES O=C(Nc1nccs1)c1cc(nc2ccccc12)-c1ccccn1
Show InChI InChI=1S/C18H12N4OS/c23-17(22-18-20-9-10-24-18)13-11-16(15-7-3-4-8-19-15)21-14-6-2-1-5-12(13)14/h1-11H,(H,20,22,23)
UniProtKB/SwissProt

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Similars
Article
PubMed
n/an/a>2.50E+5n/an/an/an/an/an/a



International Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...

Eur J Med Chem 146: 60-67 (2018)


Article DOI: 10.1016/j.ejmech.2017.11.032
BindingDB Entry DOI: 10.7270/Q2P55R2F
More data for this
Ligand-Target Pair