Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'rRNA adenine N-6-methyltransferase' and Ligand = 'BDBM50292308'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292308 (CHEMBL4164726) Show SMILES O=C(NC1CCN(CC1)c1nc2ccccc2s1)c1ccncc1 Show InChI InChI=1S/C18H18N4OS/c23-17(13-5-9-19-10-6-13)20-14-7-11-22(12-8-14)18-21-15-3-1-2-4-16(15)24-18/h1-6,9-10,14H,7-8,11-12H2,(H,20,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
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