Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM108418 (US8604206, 13 | US8604206, 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.900 | n/a | 17.1 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent... | US Patent US8604206 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM108418 (US8604206, 13 | US8604206, 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4 | n/a | 7 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent... | US Patent US8604206 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM108418 (US8604206, 13 | US8604206, 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 16 | n/a | 38 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent... | US Patent US8604206 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM108418 (US8604206, 13 | US8604206, 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 49.8 | n/a | 94.6 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent... | US Patent US8604206 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RDR | |||||||||||
More data for this Ligand-Target Pair |