BindingDB PrimarySearch

Found 19 hits of ic50 for monomerid = 50014407
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.447	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 3 receptor				J Med Chem 39: 2068-80 (1996) Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B/3C/3D/3E (Homo sapiens (Human))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.447	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligand				J Med Chem 42: 4362-79 (1999) BindingDB Entry DOI: 10.7270/Q2S75FJM
Universita' degli Studi di Salerno Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
Universit£ di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	61.7	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2C receptor				J Med Chem 39: 2068-80 (1996) Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	61.7	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity against 5-Hydroxytryptamine 2C Receptor was measured using [3H]N-methyl-mesulergine as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptor				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
Universit£ di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of radiolabeled [3H]mesulergine ligand binding to 5-hydroxytryptamine 2C receptor				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
Universit£ di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of radiolabeled [3H]-Ketanserin ligand binding to 5-hydroxytryptamine 2A receptor				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
Universit£ di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor was measured using [3H]8-OH-DPAT as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 1A receptor				J Med Chem 39: 2068-80 (1996) Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of radiolabeled [3H]-8-OH-DPAT ligand binding to 5-hydroxytryptamine 1A receptor				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
Universit£ di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (BOVINE)	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor was measured using [3H]ketanserin as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (BOVINE)	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2A receptor				J Med Chem 39: 2068-80 (1996) Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Sus scrofa)	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor was measured using [3H]5-HT as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Sus scrofa)	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 1D receptor				J Med Chem 39: 2068-80 (1996) Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 1B receptor				J Med Chem 39: 2068-80 (1996) Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1B receptor was measured using [3H]5-HT as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
Universit£ de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (RAT)	BDBM50014407 (2-(piperazin-1-yl)quinoline \| 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of radiolabeled [3H]GR-113808 ligand binding to 5-hydroxytryptamine 4 receptor				J Med Chem 40: 3670-8 (1997) Article DOI: 10.1021/jm970376w BindingDB Entry DOI: 10.7270/Q24Q7VP2
Universit£ di Siena Curated by ChEMBL					More data for this Ligand-Target Pair