| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
|---|
| Ligand | BDBM50014407 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2255 (CHEMBL873476) |
|---|
| IC50 | 3467.37±n/a nM |
|---|
| Citation |  Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Novel selective and partial agonists of 5-HT3 receptors. Part 1. Synthesis and biological evaluation of piperazinopyrrolothienopyrazines. J Med Chem39:2068-80 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2A |
|---|
| Name: | 5-hydroxytryptamine receptor 2A |
|---|
| Synonyms: | 5-HT2A | 5HT2A_BOVIN | 5HTR2A | HTR2A | Serotonin 2a (5-HT2a) receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 52578.24 |
|---|
| Organism: | BOVINE |
|---|
| Description: | 5-HT2A HTR2A BOVINE::Q75Z89 |
|---|
| Residue: | 470 |
|---|
| Sequence: | MDILCEENTSLSSTTNSLMQLHADTRLYSTDFNSGEGNTSNAFNWTVDSENRTNLSCEGC
LSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSTLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADENFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRTKLASFSFLPQSSLSSEKLFQRSIH
REPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNRDVIEAL
LNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKS
SQLQMGPKKNSKKDDKTTDNDCTMVALGKEHPEDAPADSSNTVNEKVSCV
|
|
|
|---|
| BDBM50014407 |
|---|
| n/a |
|---|
| Name | BDBM50014407 |
|---|
| Synonyms: | 2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-quinoline | 2-Piperazin-1-yl-quinoline (Quipazine) | 2-Piperazin-1-yl-quinoline(Quipazine) | CHEMBL18772 | QUIPAZINE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H15N3 |
|---|
| Mol. Mass. | 213.2783 |
|---|
| SMILES | C1CN(CCN1)c1ccc2ccccc2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
