Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mas-related G-protein coupled receptor member X2 (Homo sapiens (Human)) | BDBM50019351 ((-)-Codeine | (Codeine) | (codeine)10-methoxy-4-me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.80E+3 | n/a | n/a | 7.4 | 30 |
University of North Carolina | Assay Description HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor... | Nat Chem Biol 13: 529-536 (2017) Article DOI: 10.1038/nchembio.2334 BindingDB Entry DOI: 10.7270/Q20R9N82 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mas-related G-protein coupled receptor member X2 (Homo sapiens (Human)) | BDBM50019351 ((-)-Codeine | (Codeine) | (codeine)10-methoxy-4-me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | 7.4 | 30 |
University of North Carolina | Assay Description MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza... | Nat Chem Biol 13: 529-536 (2017) Article DOI: 10.1038/nchembio.2334 BindingDB Entry DOI: 10.7270/Q20R9N82 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type/Kappa-type/Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50019351 ((-)-Codeine | (Codeine) | (codeine)10-methoxy-4-me...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.00E+5 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to opiate receptor in rat brain homogenates | J Med Chem 22: 328-31 (1979) Article DOI: 10.1021/jm00189a024 BindingDB Entry DOI: 10.7270/Q2GH9MX3 | |||||||||||
More data for this Ligand-Target Pair |