Compile Data Set for Download or QSAR

Found 71 hits of ic50 for monomerid = 50180787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L117A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q208E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR W291F				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.8	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189P				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.8	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K191E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.2	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186D				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13.1	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13.6	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.6	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.1	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.2	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168I				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.2	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.7	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.7	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR T51A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16.2	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q208D				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16.9	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F272L				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17.7	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from human wild type GnRHR				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR A50T				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17.9	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.8	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR T190K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20.6	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21.3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S124A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22.4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23.2	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24I				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23.3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H306A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24.2	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K115Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27.2	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27.3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302N				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28.8	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y284F				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112F				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32.6	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293N				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.6	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290F				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41.4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203P				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair

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