Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM84978 (Quercitrin | cid_5280459) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Monash University Curated by ChEMBL | Assay Description Inhibition of human recombinant aldose reductase | Bioorg Med Chem 16: 3245-54 (2008) Article DOI: 10.1016/j.bmc.2007.12.016 BindingDB Entry DOI: 10.7270/Q2PZ59P2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine Curated by ChEMBL | Assay Description Inhibition of rat lens aldose reductase | J Nat Prod 71: 713-5 (2008) Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM84978 (Quercitrin | cid_5280459) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
King's College London Curated by ChEMBL | Assay Description Inhibition of human recombinant aldose reductase using D-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured for ... | Bioorg Med Chem 20: 1251-8 (2012) Article DOI: 10.1016/j.bmc.2011.12.033 BindingDB Entry DOI: 10.7270/Q2639Q5V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PC4 and SFRS1-interacting protein (Homo sapiens (Human)) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 2.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam... | PubChem Bioassay (2014) BindingDB Entry DOI: 10.7270/Q2KD1WKS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 [K65Q] (Bos taurus (Cattle)) | BDBM84978 (Quercitrin | cid_5280459) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro inhibition of partially purified calf lens aldose reductase; value ranges from 10E-5 to 10E-6 | J Med Chem 31: 230-43 (1988) BindingDB Entry DOI: 10.7270/Q27D2VQF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase (Leishmania amazonensis) | BDBM84978 (Quercitrin | cid_5280459) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal de S£o Carlos Curated by ChEMBL | Assay Description Inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substrate incubated f... | J Nat Prod 77: 392-6 (2014) Article DOI: 10.1021/np400717m BindingDB Entry DOI: 10.7270/Q2VX0J09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PC4 and SFRS1-interacting protein (Homo sapiens (Human)) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam... | PubChem Bioassay (2014) BindingDB Entry DOI: 10.7270/Q2Q52N9H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 10 (Homo sapiens (Human)) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.02E+4 | n/a | n/a | n/a | n/a | n/a | 37 |
Eberhard Karls University of Tuebingen | Assay Description The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n... | Chembiochem 11: 2579-88 (2010) Article DOI: 10.1002/cbic.201000487 BindingDB Entry DOI: 10.7270/Q21C1VDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human)) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University Curated by ChEMBL | Assay Description Inhibition of Pim2 kinase | J Nat Prod 71: 451-2 (2008) Article DOI: 10.1021/np070431w BindingDB Entry DOI: 10.7270/Q25M66KR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.81E+4 | n/a | n/a | n/a | n/a | n/a | 37 |
Eberhard Karls University of Tuebingen | Assay Description The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n... | Chembiochem 11: 2579-88 (2010) Article DOI: 10.1002/cbic.201000487 BindingDB Entry DOI: 10.7270/Q21C1VDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C21 (Mus musculus) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Monash University Curated by ChEMBL | Assay Description Inhibition of mouse recombinant AKR1C21 | Bioorg Med Chem 16: 3245-54 (2008) Article DOI: 10.1016/j.bmc.2007.12.016 BindingDB Entry DOI: 10.7270/Q2PZ59P2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Xanthine dehydrogenase/oxidase (Homo sapiens (Human)) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometry | J Nat Prod 61: 71-6 (1998) Article DOI: 10.1021/np970237h BindingDB Entry DOI: 10.7270/Q29C6Z93 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Bos taurus) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production | J Nat Prod 61: 2-7 (1998) Article DOI: 10.1021/np970343j BindingDB Entry DOI: 10.7270/Q2JS9RBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Ovis aries (Sheep)) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production | J Nat Prod 61: 2-7 (1998) Article DOI: 10.1021/np970343j BindingDB Entry DOI: 10.7270/Q2JS9RBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Bos taurus) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 mins | J Nat Prod 61: 2-7 (1998) Article DOI: 10.1021/np970343j BindingDB Entry DOI: 10.7270/Q2JS9RBH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Ovis aries (Sheep)) | BDBM84978 (Quercitrin | cid_5280459) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 mins | J Nat Prod 61: 2-7 (1998) Article DOI: 10.1021/np970343j BindingDB Entry DOI: 10.7270/Q2JS9RBH | |||||||||||
More data for this Ligand-Target Pair |