Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human)) | BDBM86248 (CAS_364-98-7 | NSC_3019 | diazoxide) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.94E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATP | J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human)) | BDBM86248 (CAS_364-98-7 | NSC_3019 | diazoxide) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 1.98E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ... | J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human)) | BDBM86248 (CAS_364-98-7 | NSC_3019 | diazoxide) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 7.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells | J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human)) | BDBM86248 (CAS_364-98-7 | NSC_3019 | diazoxide) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 7.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without... | J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM | |||||||||||
More data for this Ligand-Target Pair |