Compile Data Set for Download or QSAR

Found 1220 hits of ki for UniProtKB: P54289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572311 (CHEMBL4847725) Show SMILES CCC[C@@H](N1CCN[C@H](C)C1)c1nc2ccncc2c(=O)n1CC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572290 (CHEMBL4847873) Show SMILES CCC[C@@H](N1C[C@H](C)N[C@H](C)C1)c1nc2ccc(Br)cc2c(=O)n1CC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50410554 (CHEMBL5273513) Show SMILES Cc1ccc(NC(=O)c2[nH]c(nc2CCC23CC4CC(CC(C4)C2)C3)-c2ccccc2C)cc1C(O)=O |TLB:18:19:23:17.16.22,22:21:24:17.16.18,22:17:24:21.23.20,THB:18:17:23:19.24.20,20:19:16:21.23.22,20:21:16:19.24.18| Show InChI InChI=1S/C31H35N3O3/c1-18-5-3-4-6-24(18)28-33-26(9-10-31-15-20-11-21(16-31)13-22(12-20)17-31)27(34-28)29(35)32-23-8-7-19(2)25(14-23)30(36)37/h3-8,14,20-22H,9-13,15-17H2,1-2H3,(H,32,35)(H,33,34)(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against dihydrofolate reductase in rat liver				Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50557449 (CHEMBL4744000) Show SMILES [H][C@@]12CCCN1c1nc(NCC)ncc1C(=O)N(C2)c1cccc(c1)-c1noc(C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01867 BindingDB Entry DOI: 10.7270/Q2JW8JKT
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572295 (CHEMBL4851929) Show SMILES CCCC(N1C[C@H](C)N[C@H](C)C1)c1nc2cc(Br)ccc2c(=O)n1CC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572303 (CHEMBL4847073) Show SMILES CCC[C@@H](N1CCN[C@H](C)C1)c1nc2ccc(Br)cc2c(=O)n1CC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572289 (CHEMBL4859215) Show SMILES CCCC(N1C[C@H](C)N[C@H](C)C1)c1nc2ccc(Br)cc2c(=O)n1CC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572296 (CHEMBL4868703) Show SMILES CCCC(N1C[C@H](C)N[C@H](C)C1)c1nc2cc(ccc2c(=O)n1CC)-c1ccncc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50164279 ((S)-3-(aminomethyl)-5-methylhexanoic acid | (S)-3-...) Show SMILES CC(C)C[C@H](CN)CC(O)=O |r| Show InChI InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50164279 ((S)-3-(aminomethyl)-5-methylhexanoic acid | (S)-3-...) Show SMILES CC(C)C[C@H](CN)CC(O)=O |r| Show InChI InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01867 BindingDB Entry DOI: 10.7270/Q2JW8JKT
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572308 (CHEMBL4858331) Show SMILES CCC[C@@H](N1CCN[C@@H](C)C1)c1nc2ccncc2c(=O)n1CC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572287 (CHEMBL4854799) Show SMILES CCCC(N1C[C@H](C)N[C@H](C)C1)c1nc2ccccc2c(=O)n1CC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572294 (CHEMBL4854923) Show SMILES CCCC(N1C[C@H](C)N[C@H](C)C1)c1nc2ccc(cc2c(=O)n1CC)-c1ccncc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572293 (CHEMBL4862112) Show SMILES CCCC(N1C[C@H](C)N[C@H](C)C1)c1nc2ccc(NCC)cc2c(=O)n1CC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572297 (CHEMBL4856257) Show SMILES CCCC(N1C[C@H](C)N[C@H](C)C1)c1nc2cccc(Br)c2c(=O)n1CC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572288 (CHEMBL4853335) Show SMILES CCCC(N1C[C@H](C)N[C@H](C)C1)c1nc2ccccc2c(=O)n1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572299 (CHEMBL4854635) Show SMILES CCCC(N1CCNCC1)c1nc2ccc(Br)cc2c(=O)n1CC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM436318 (2-(ethylamino)-9- methyl-6-(3-(5-methyl- 1,3,4-oxa...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-c1nnc(C)o1)C2=O Show InChI InChI=1S/C19H21N7O2/c1-4-20-19-21-11-15-16(22-19)25(3)8-9-26(18(15)27)14-7-5-6-13(10-14)17-24-23-12(2)28-17/h5-7,10-11H,4,8-9H2,1-3H3,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01867 BindingDB Entry DOI: 10.7270/Q2JW8JKT
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50572302 (CHEMBL4864739) Show SMILES CCC[C@@H](N1CCN[C@@H](C)C1)c1nc2ccc(Br)cc2c(=O)n1CC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00416 BindingDB Entry DOI: 10.7270/Q2GX4GCH
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM485711 ((S)-N-methyl-3-(quinolin- 5-yloxy)-3-(thiophen-2- ...) Show SMILES CNCC[C@H](Oc1cccc2ncccc12)c1cccs1 |r| Show InChI InChI=1S/C17H18N2OS/c1-18-11-9-16(17-8-4-12-21-17)20-15-7-2-6-14-13(15)5-3-10-19-14/h2-8,10,12,16,18H,9,11H2,1H3/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10941138 (2021) BindingDB Entry DOI: 10.7270/Q2XW4NXF
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436621 ((S)-2-methoxy-9- methyl-6-(2-methyl- 4-(3-(methyla...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)c(C)c1)c1cccs1 |r| Show InChI InChI=1S/C25H31N5O3S/c1-17-14-19(33-21(9-10-26-2)22-6-5-13-34-22)8-7-18(17)16-30-12-11-29(3)23-20(24(30)31)15-27-25(28-23)32-4/h5-8,13-15,21,26H,9-12,16H2,1-4H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436625 ((S)-6-(2-fluoro-4-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)c(F)c1)c1cccs1 |r| Show InChI InChI=1S/C24H28FN5O3S/c1-26-9-8-20(21-5-4-12-34-21)33-17-7-6-16(19(25)13-17)15-30-11-10-29(2)22-18(23(30)31)14-27-24(28-22)32-3/h4-7,12-14,20,26H,8-11,15H2,1-3H3/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436666 (6-(3-(5-((4- (dimethylamino)-4-(3- hydroxyphenyl)p...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-c1nnc(CN3CCC(CC3)(N(C)C)c3cccc(O)c3)o1)C2=O Show InChI InChI=1S/C32H39N9O3/c1-5-33-31-34-20-26-28(35-31)39(4)16-17-41(30(26)43)24-10-6-8-22(18-24)29-37-36-27(44-29)21-40-14-12-32(13-15-40,38(2)3)23-9-7-11-25(42)19-23/h6-11,18-20,42H,5,12-17,21H2,1-4H3,(H,33,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436666 (6-(3-(5-((4- (dimethylamino)-4-(3- hydroxyphenyl)p...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-c1nnc(CN3CCC(CC3)(N(C)C)c3cccc(O)c3)o1)C2=O Show InChI InChI=1S/C32H39N9O3/c1-5-33-31-34-20-26-28(35-31)39(4)16-17-41(30(26)43)24-10-6-8-22(18-24)29-37-36-27(44-29)21-40-14-12-32(13-15-40,38(2)3)23-9-7-11-25(42)19-23/h6-11,18-20,42H,5,12-17,21H2,1-4H3,(H,33,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436318 (2-(ethylamino)-9- methyl-6-(3-(5-methyl- 1,3,4-oxa...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-c1nnc(C)o1)C2=O Show InChI InChI=1S/C19H21N7O2/c1-4-20-19-21-11-15-16(22-19)25(3)8-9-26(18(15)27)14-7-5-6-13(10-14)17-24-23-12(2)28-17/h5-7,10-11H,4,8-9H2,1-3H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM432250 (N-{1-[3-(5-Methyl-1,3,4-oxadiazol-2-yl)phenyl]-1H-...) Show SMILES CN1CCC(CC1)N(C(=O)c1cccs1)c1ccn(n1)-c1cccc(c1)-c1nnc(C)o1 Show InChI InChI=1S/C23H24N6O2S/c1-16-24-25-22(31-16)17-5-3-6-19(15-17)28-13-10-21(26-28)29(18-8-11-27(2)12-9-18)23(30)20-7-4-14-32-20/h3-7,10,13-15,18H,8-9,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				US Patent US10577360 (2020) BindingDB Entry DOI: 10.7270/Q2MC92DM
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562282 ((S)-4-(2-fluoro-4-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(F)c1)c1cccs1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562290 ((S)-4-(2-fluoro-4-(3- (methylamino)-1- phenylpropo...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(F)c1)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562295 ((S)-4-(3-fluoro-5-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCCC(Oc1cc(F)cc(c1)N1CCN(C)c2ncccc2C1=O)c1cccs1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562296 (4-(3-Fluoro-5-(1-(3- fluorophenyl)-3- (methylamino...) Show SMILES CNCCC(Oc1cc(F)cc(c1)N1CCN(C)c2ncccc2C1=O)c1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562298 (4-(2-Fluoro-4-(1-(3- fluorophenyl)-3- (methylamino...) Show SMILES CNCCC(Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(F)c1)c1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562301 ((S)-4-(2-chloro-4-( 3- (methylamino)-1- (thiophen-...) Show SMILES CN1CCN(Cc2ccc(O[C@@H](CCN)c3cccs3)cc2Cl)C(=O)c2cccnc12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562306 (8-Amino-4-(2-fluoro-4- (1-(3-fluorophenyl)-3- (met...) Show SMILES CNCCC(Oc1ccc(CN2CCN(C)c3nc(N)ccc3C2=O)c(F)c1)c1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562309 ((S)-2-methoxy-5-(2- methyl-4-(3- (methylamino)-1- ...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCCn3nc(OC)cc3C2=O)c(C)c1)c1cccs1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562311 ((S)-4-(2-fluoro-4-(1-(3- fluorophenyl)-3- (methyla...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(F)c1)c1cccc(F)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562313 ((S)-8-amino-4-(2-chloro- 4-(3-(methylamino)-1- phe...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(N)ccc3C2=O)c(Cl)c1)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562315 ((S)-4-(2-fluoro-4-(3- (methylamino)-1- phenylpropo...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3cnc(OC)cc3C2=O)c(F)c1)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562316 ((S)-(2-chloro-4-(3- (methylamino)-1- phenylpropoxy...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(Cl)c1)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562324 ((S)-4-(2-chloro-4-(1-(3- fluorophenyl)-3- (methyla...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(Cl)c1)c1cccc(F)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562327 ((S)-4-(2-fluoro-4-(1-(2- fluorophenyl)-3- (methyla...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(F)c1)c1ccccc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562328 ((S)-8-amino-4-(2-fluoro- 4-(1-(3-fluorophenyl)-3- ...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(N)ccc3C2=O)c(F)c1)c1cccc(F)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562273 (1-Methyl-4-(4-(3- (methylamino)-1- (thiophen-2- yl...) Show SMILES CNCCC(Oc1ccc(CN2CCN(C)c3ncccc3C2=O)cc1)c1cccs1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562277 ((S)-8-amino-1-methyl- 4-(4-(3-(methylamino)- 1-(th...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(N)ccc3C2=O)cc1)c1cccs1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562281 ((S)-1-methyl-4-(2- methyl-4-(3- (methylamino)-1- (...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(C)c1)c1cccs1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562282 ((S)-4-(2-fluoro-4-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(F)c1)c1cccs1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562290 ((S)-4-(2-fluoro-4-(3- (methylamino)-1- phenylpropo...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(F)c1)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562295 ((S)-4-(3-fluoro-5-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCCC(Oc1cc(F)cc(c1)N1CCN(C)c2ncccc2C1=O)c1cccs1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562296 (4-(3-Fluoro-5-(1-(3- fluorophenyl)-3- (methylamino...) Show SMILES CNCCC(Oc1cc(F)cc(c1)N1CCN(C)c2ncccc2C1=O)c1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562298 (4-(2-Fluoro-4-(1-(3- fluorophenyl)-3- (methylamino...) Show SMILES CNCCC(Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(F)c1)c1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM562299 ((S)-2-methyl-5-(2- methyl-4-(3- (methylamino)-1- (...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCCn3nc(C)cc3C2=O)c(C)c1)c1cccs1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PC35MW
					More data for this Ligand-Target Pair

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