Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingomyelinase C (Bacillus cereus) | BDBM248063 (SMY-540) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.30E+3 | -8.35 | 800 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248063 (SMY-540) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assay | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248061 (SMY-471) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.80E+3 | -7.87 | 900 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248061 (SMY-471) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assay | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248057 (RY221B-a) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.20E+3 | -7.49 | 1.20E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248057 (RY221B-a) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assay | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248064 (SMY-610) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248062 (SMY-579) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.83E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248068 (TOM-2-37) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248067 (TOM-2-18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248066 (TOM-2-7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248065 (SMY-469a) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248060 (SMY-632) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248059 (SMY-584) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM248058 (RY221B-b) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Tokushima Bunri University | Assay Description Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix... | J Enzyme Inhib Med Chem 29: 303-10 (2014) Article DOI: 10.3109/14756366.2013.777717 BindingDB Entry DOI: 10.7270/Q2NV9H50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM50407393 (CHEMBL5287935) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assay | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM50407394 (CHEMBL5282509) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assay | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM50407392 (CHEMBL5267896) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assay | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelinase C (Bacillus cereus) | BDBM50407391 (CHEMBL5289378) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assay | Citation and Details | |||||||||||
More data for this Ligand-Target Pair |