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Compile Data Set for Download or QSAR

Found 2 hits of kd for UniProtKB: P00751   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM160475
PNG
(US10093663, Example 26b | US9682968, Example-26a)
Show SMILES CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(O)=O |r|
PDB

UniProtKB/SwissProt

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MCE
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/an/a 7.90n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Binding affinity to human serine protease factor B by SPR assay


J Med Chem 63: 5697-5722 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01870
BindingDB Entry DOI: 10.7270/Q21N84P4
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM50540286
PNG
(CHEMBL4636550)
Show SMILES Cc1cc(Br)c(NC2=NCCN2)c2ccccc12 |t:7|
Show InChI InChI=1S/C14H14BrN3/c1-9-8-12(15)13(18-14-16-6-7-17-14)11-5-3-2-4-10(9)11/h2-5,8H,6-7H2,1H3,(H2,16,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/an/a 1.00E+4n/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Binding affinity to human serine protease factor B by SPR assay


J Med Chem 63: 5697-5722 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01870
BindingDB Entry DOI: 10.7270/Q21N84P4
More data for this
Ligand-Target Pair