Compile Data Set for Download or QSAR

Found 255 hits of ic50 for UniProtKB: P03372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521345 (4-(2-fluoro-4- hydroxy- phenyl)-5-[4- [(3S)-1-(3- ...) Show SMILES Oc1ccc(c(F)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SCC1 |r,c:9| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521334 (5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...) Show SMILES Oc1cccc(c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SCC1 |r,c:8| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521421 (6-(2,4- dichlorophenyl)- 1-fluoro-5-[6- [(3S)-1-(3...) Show SMILES Oc1ccc2c(CCCC(c3ccc(Cl)cc3Cl)=C2c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c1F |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521296 (4-(benzofuran- 5-yl)-5-[4-[(3S)- 1-(3- fluoropropy...) Show SMILES Oc1ccc2c(OCCC(c3ccc4occc4c3)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:20| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521416 (6-(6-ethoxy-2- fluoro-3- pyridyl)-5-[6- [(3S)-1-(3...) Show SMILES CCOc1ccc(c(F)n1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c2ccc(O)cc2CCC1 |r,c:11| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521360 (4-(benzofuran- 5-yl)-5-[4-[(3S)- 1-(3- fluoropropy...) Show SMILES Oc1ccc2c(SCCC(c3ccc4occc4c3)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:20| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521255 (3-(6-ethoxy-2- fluoro-3- pyridyl)-4-[6- [(3S)-1-(3...) Show SMILES CCOc1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)nc3)c3ccc(O)cc3SC2)c(F)n1 |r,c:7| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521384 (4-(6-ethoxy-2- fluoro-3- pyridyl)-5-[6- [(3S)-1-(3...) Show SMILES CCOc1ccc(c(F)n1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c2ccc(O)cc2SCC1 |r,c:11| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521413 (6-(2-fluoro-4- methyl-phenyl)- 5-[6-[(3S)-1-(3- fl...) Show SMILES Cc1ccc(c(F)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c2ccc(O)cc2CCC1 |r,c:9| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521262 (6-(6-ethoxy-2- fluoro-3- pyridyl)-5-[4- [[(3S)-1-(...) Show SMILES CCOc1ccc(c(F)n1)C1=C(c2ccc(N[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2CCC1 |r,c:11| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521270 (4-(2-fluoro-4- hydroxy- phenyl)-5-[4- [(3S)-1-(3- ...) Show SMILES Oc1ccc(c(F)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2OCC1 |r,c:9| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521383 (4-[4- (difluoromethoxy)- 3-fluoro- phenyl]-5-[6- [...) Show SMILES Oc1ccc2c(SCCC(c3ccc(OC(F)F)c(F)c3)=C2c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c1 |r,c:21| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521295 (4-(4-ethoxy-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...) Show SMILES CCOc1ccc(c(C)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2OCC1 |r,c:11| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521374 (4-(2,2- dimethylindolin- 5-yl)-5-[4-[(3S)- 1-(3- f...) Show SMILES CC1(C)Cc2cc(ccc2S1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SCC1 |r,c:13| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521267 (5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...) Show SMILES Oc1cccc(c1)C1=C(c2ccc(N[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2OCC1 |r,c:8| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521192 (3-(2-fluoro-4- methyl-phenyl)- 4-[4-[(3S)-1-(3- fl...) Show SMILES Cc1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)cc3)c3ccc(O)cc3SC2)c(F)c1 |r,c:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521354 (5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...) Show SMILES Oc1ccc2c(SCCC(c3cccc4[nH]ccc34)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:20| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521418 (6-(2,2- dimethylindolin- 5-yl)-5-[6-[(3S)- 1-(3- f...) Show SMILES CC1(C)Cc2cc(ccc2N1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c2ccc(O)cc2CCC1 |r,c:13| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521182 (7-(2-fluoro-4- hydroxy- phenyl)-8-[4- [(3S)-1-(3- ...) Show SMILES Oc1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)cc3)c3cc(O)ccc3CC2)c(F)c1 |r,c:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521341 (4-(4-fluoro-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...) Show SMILES Cc1cc(F)ccc1C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SCC1 |r,c:9| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521336 (5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...) Show SMILES Oc1ccc2c(SCCC(c3ccc4[nH]ccc4c3)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:20| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521198 (3-(2-chloro-4- fluoro-phenyl)- 4-[4-[(3S)-1-(3- fl...) Show SMILES Oc1ccc2C(=C(CSc2c1)c1ccc(F)cc1Cl)c1ccc(O[C@H]2CCN(CCCF)C2)cc1 |r,c:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521415 (6-(2,4- dichlorophenyl)- 5-[6-[(3S)-1-(3- fluoropr...) Show SMILES Oc1ccc2c(CCCC(c3ccc(Cl)cc3Cl)=C2c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c1 |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521382 (4-(2-chloro-4- methyl-phenyl)- 5-[6-[(3S)-1-(3- fl...) Show SMILES Cc1ccc(c(Cl)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c2ccc(O)cc2SCC1 |r,c:9| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521344 (4-(2-chloro-3- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...) Show SMILES Oc1ccc2c(SCCC(c3cccc(F)c3Cl)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521428 (6-(6-ethoxy-2- fluoro-3- pyridyl)-1- fluoro-5-[6- ...) Show SMILES CCOc1ccc(c(F)n1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c2ccc(O)c(F)c2CCC1 |r,c:11| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521340 (4-(2-fluoro-4- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...) Show SMILES Cc1ccc(c(F)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SCC1 |r,c:9| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521335 (4-(2-chloro-4- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...) Show SMILES Oc1ccc2c(SCCC(c3ccc(F)cc3Cl)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521378 (5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...) Show SMILES C[C@@H]1Cc2cc(ccc2O1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SCC1 |r,c:12| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521381 (4-(2,4- dichlorophenyl)- 5-[(6-[(3S)-1-(3- fluorop...) Show SMILES Oc1ccc2c(SCCC(c3ccc(Cl)cc3Cl)=C2c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c1 |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521195 (4-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...) Show SMILES Oc1ccc2C(=C(CSc2c1)c1ccc2[nH]ccc2c1)c1ccc(O[C@H]2CCN(CCCF)C2)cc1 |r,c:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521297 (4-(2-fluoro-4- methoxy- phenyl)-5-[4- [(3S)-1-(3- ...) Show SMILES COc1ccc(c(F)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2OCC1 |r,c:10| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521373 (5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...) Show SMILES CC1Cc2cc(ccc2O1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SCC1 |r,c:12| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521425 (6-[4- (difluoromethoxy)- 3-fluoro- phenyl]-1- fluo...) Show SMILES Oc1ccc2c(CCCC(c3ccc(OC(F)F)c(F)c3)=C2c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c1F |r,c:21| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521221 (3-(2-fluoro-6- methoxy-3- pyridyl)-4-[4- [(3S)-1-(...) Show SMILES COc1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)cc3)c3ccc(O)cc3SC2)c(F)n1 |r,c:6| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521193 (3-(4-chloro-3- methyl-phenyl)- 4-[4-[(3S)-1-(3- fl...) Show SMILES Cc1cc(ccc1Cl)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SC1 |r,c:9| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521377 (4-(2,2-dimethyl- 3H-benzofuran- 5-yl)-5-[4-[(3S)- ...) Show SMILES CC1(C)Cc2cc(ccc2O1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SCC1 |r,c:13| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521380 (5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...) Show SMILES C[C@H]1Cc2cc(ccc2O1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SCC1 |r,c:12| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521261 (6-(2,4- dichlorophenyl)- 5-[4-[[(3S)-1- (3- fluoro...) Show SMILES Oc1ccc2c(CCCC(c3ccc(Cl)cc3Cl)=C2c2ccc(N[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521254 (3-(2-fluoro-4- methyl-phenyl)- 4-[6-[(3S)-1-(3- fl...) Show SMILES Cc1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)nc3)c3ccc(O)cc3SC2)c(F)c1 |r,c:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521194 (3-(4-chloro-2- fluoro-phenyl)- 4-[4-[(3S)-1-(3- fl...) Show SMILES Oc1ccc2C(=C(CSc2c1)c1ccc(Cl)cc1F)c1ccc(O[C@H]2CCN(CCCF)C2)cc1 |r,c:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521343 (4-(4-chloro-2- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...) Show SMILES Oc1ccc2c(SCCC(c3ccc(Cl)cc3F)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521356 (4-(4-fluoro-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...) Show SMILES Cc1cc(F)ccc1C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2cc(O)ccc2SCC1 |r,c:9| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521282 (9-fluoro-4-(2- fluoro-4-methyl- phenyl)-5-[4- [(3S...) Show SMILES Cc1ccc(c(F)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)c(F)c2OCC1 |r,c:9| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521417 (6-[4- (difluoromethoxy)- 3-fluoro- phenyl]-5-[6- [...) Show SMILES Oc1ccc2c(CCCC(c3ccc(OC(F)F)c(F)c3)=C2c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c1 |r,c:21| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521362 (4-(4-ethoxy-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...) Show SMILES CCOc1ccc(c(C)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2SCC1 |r,c:11| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521273 (4-(4-chloro-3- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...) Show SMILES Oc1ccc2c(OCCC(c3ccc(Cl)c(F)c3)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521348 (5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...) Show SMILES Oc1ccc2c(SCCC(c3ccc4cc[nH]c4c3)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:20| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521297 (4-(2-fluoro-4- methoxy- phenyl)-5-[4- [(3S)-1-(3- ...) Show SMILES COc1ccc(c(F)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2OCC1 |r,c:10| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521197 (3-(2,4- dichlorophenyl)- 4-[4-[(3S)-1-(3- fluoropr...) Show SMILES Oc1ccc2C(=C(CSc2c1)c1ccc(Cl)cc1Cl)c1ccc(O[C@H]2CCN(CCCF)C2)cc1 |r,c:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair

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