Compile Data Set for Download or QSAR

Found 143 hits of ic50 for UniProtKB: P00533   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525534 (US11174245, # I-211) Show SMILES Cn1cc(cn1)-c1cc(cc(N)n1)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:25.28,28.32,(4.48,-3.56,;5.25,-2.23,;4.35,-.98,;5.25,.26,;6.72,-.21,;6.72,-1.75,;4.48,1.6,;2.94,1.6,;2.17,2.93,;2.94,4.26,;4.48,4.26,;5.25,5.6,;5.25,2.93,;.63,2.93,;-.14,4.26,;-.14,1.6,;-1.68,1.6,;-2.58,2.84,;-4.05,2.37,;-5.38,3.14,;-6.72,2.37,;-6.72,.83,;-5.38,.06,;-4.05,.83,;-2.58,.35,;-2.19,-1.14,;-3.27,-2.22,;-2.88,-3.71,;-1.39,-4.11,;-.99,-5.6,;-.3,-3.02,;-.7,-1.53,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525547 (US11174245, # I-225) Show SMILES CN1CCC(CC1)c1ccc2[nH]\c(=N/C(=O)c3cc(C)nc(c3)-c3cnn(C)c3)n([C@@H]3CC[C@H](O)CC3)c2c1 |r,wU:30.32,33.36,(-9.66,-2.25,;-8.33,-1.48,;-8.33,.06,;-6.99,.83,;-5.66,.06,;-5.66,-1.48,;-6.99,-2.25,;-4.32,.83,;-4.32,2.37,;-2.99,3.14,;-1.66,2.37,;-.19,2.84,;.71,1.6,;2.25,1.6,;3.02,2.93,;2.25,4.26,;4.56,2.93,;5.33,4.26,;6.87,4.26,;7.64,5.6,;7.64,2.93,;6.87,1.6,;5.33,1.6,;7.64,.26,;9.18,.26,;9.66,-1.2,;8.41,-2.11,;8.41,-3.65,;7.17,-1.2,;-.19,.35,;.21,-1.14,;-.88,-2.22,;-.48,-3.71,;1,-4.11,;1.4,-5.6,;2.09,-3.02,;1.69,-1.53,;-1.66,.83,;-2.99,.06,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525456 (US11174245, # I-048) Show SMILES Cn1cc(cn1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:24.27,27.31,(5.75,-2.98,;5.75,-1.44,;4.5,-.53,;4.98,.93,;6.52,.93,;6.99,-.53,;4.21,2.26,;2.67,2.26,;1.9,3.6,;2.67,4.93,;4.21,4.93,;4.98,3.6,;.36,3.6,;-.41,4.93,;-.41,2.26,;-1.95,2.26,;-2.86,3.51,;-4.32,3.03,;-5.66,3.8,;-6.99,3.03,;-6.99,1.49,;-5.66,.72,;-4.32,1.49,;-2.86,1.02,;-2.46,-.47,;-3.55,-1.56,;-3.15,-3.05,;-1.66,-3.44,;-1.27,-4.93,;-.57,-2.36,;-.97,-.87,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525541 (US11174245, # I-219) Show SMILES CC(=O)N1CCC(CC1)c1ccc2n([C@@H]3CC[C@H](O)CC3)\c(=N\C(=O)c3ccnc(c3)-c3cnn(C)c3)[nH]c2c1 |r,wU:14.14,17.18,(-10.33,3.98,;-8.99,4.75,;-8.99,6.29,;-7.66,3.98,;-6.32,4.75,;-4.99,3.98,;-4.99,2.44,;-6.32,1.67,;-7.66,2.44,;-3.66,1.67,;-3.66,.13,;-2.32,-.64,;-.99,.13,;.47,-.34,;.87,-1.83,;-.22,-2.92,;.18,-4.41,;1.67,-4.81,;2.07,-6.29,;2.76,-3.72,;2.36,-2.23,;1.38,.9,;2.92,.9,;3.69,2.24,;2.92,3.57,;5.23,2.24,;6,3.57,;7.54,3.57,;8.31,2.24,;7.54,.9,;6,.9,;8.31,-.43,;9.85,-.43,;10.33,-1.9,;9.08,-2.8,;9.08,-4.34,;7.83,-1.9,;.47,2.15,;-.99,1.67,;-2.32,2.44,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525546 (US11174245, # I-224) Show SMILES CN1CCN(Cc2ccc3[nH]\c(=N/C(=O)c4cc(C)nc(c4)-c4cnn(C)c4)n(C4CCCCC4)c3c2)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525472 (US11174245, # I-109) Show SMILES COc1ccccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2cc(C)ccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:27.30,30.34,(2.42,-1.74,;3.19,-.4,;4.73,-.4,;5.5,-1.74,;7.04,-1.74,;7.81,-.4,;7.04,.93,;5.5,.93,;4.73,2.26,;3.19,2.26,;2.42,3.6,;3.19,4.93,;4.73,4.93,;5.5,3.6,;.88,3.6,;.11,4.93,;.11,2.26,;-1.43,2.26,;-2.34,3.51,;-3.8,3.03,;-5.14,3.8,;-6.47,3.03,;-7.81,3.8,;-6.47,1.49,;-5.14,.72,;-3.8,1.49,;-2.34,1.02,;-1.94,-.47,;-3.03,-1.56,;-2.63,-3.05,;-1.14,-3.44,;-.75,-4.93,;-.06,-2.36,;-.45,-.87,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525471 (US11174245, # I-108) Show SMILES COc1ccccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:26.29,29.33,(1.75,-1.74,;2.52,-.4,;4.06,-.4,;4.83,-1.74,;6.37,-1.74,;7.14,-.4,;6.37,.93,;4.83,.93,;4.06,2.26,;2.52,2.26,;1.75,3.6,;2.52,4.93,;4.06,4.93,;4.83,3.6,;.21,3.6,;-.56,4.93,;-.56,2.26,;-2.1,2.26,;-3.01,3.51,;-4.47,3.03,;-5.8,3.8,;-7.14,3.03,;-7.14,1.49,;-5.8,.72,;-4.47,1.49,;-3.01,1.02,;-2.61,-.47,;-3.7,-1.56,;-3.3,-3.05,;-1.81,-3.44,;-1.41,-4.93,;-.72,-2.36,;-1.12,-.87,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525544 (US11174245, # I-222) Show SMILES CN1CCN(Cc2ccc3[nH]\c(=N/C(=O)c4cc(C)nc(c4)-c4cnn(C)c4)n([C@@H]4CC[C@H](O)CC4)c3c2)CC1 |r,wU:29.30,32.34,(-9.97,-5.04,;-8.43,-5.04,;-7.66,-3.71,;-6.12,-3.71,;-5.35,-5.04,;-3.81,-5.04,;-3.04,-3.71,;-3.81,-2.37,;-3.04,-1.04,;-1.5,-1.04,;-.47,.11,;.93,-.52,;2.27,.25,;2.27,1.79,;.93,2.56,;3.6,2.56,;3.6,4.1,;4.94,4.87,;4.94,6.41,;6.27,4.1,;6.27,2.56,;4.94,1.79,;7.6,1.79,;9.07,2.26,;9.97,1.02,;9.07,-.23,;9.84,-1.56,;7.6,.25,;.77,-2.05,;1.86,-3.14,;1.46,-4.63,;2.55,-5.72,;4.04,-5.32,;5.13,-6.41,;4.44,-3.83,;3.35,-2.74,;-.73,-2.37,;-1.5,-3.71,;-6.12,-6.37,;-7.66,-6.37,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525469 (US11174245, # I-105) Show SMILES COc1ccccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1CC(C)(C)O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525462 (US11174245, # I-060) Show SMILES COc1ccccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2cc(CN3CCOCC3)ccc2n1CC(C)(C)O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525479 (US11174245, # I-116 | US11174245, # I-137) Show SMILES Cn1cc(cn1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@H]1CCC[C@H](O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525480 (US11174245, # I-118) Show SMILES COc1ccccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@H]1CCC[C@@H](O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525479 (US11174245, # I-116 | US11174245, # I-137) Show SMILES Cn1cc(cn1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@H]1CCC[C@H](O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525486 (US11174245, # I-136 | US11174245, # I-138) Show SMILES Cn1cc(cn1)-c1cc(cc(n1)C#N)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:26.29,29.33,(5.75,-4.31,;5.75,-2.77,;4.5,-1.87,;4.98,-.4,;6.52,-.4,;6.99,-1.87,;4.21,.93,;2.67,.93,;1.9,2.26,;2.67,3.6,;4.21,3.6,;4.98,2.26,;4.98,4.93,;5.75,6.27,;.36,2.26,;-.41,3.6,;-.41,.93,;-1.95,.93,;-2.86,2.18,;-4.32,1.7,;-5.66,2.47,;-6.99,1.7,;-6.99,.16,;-5.66,-.61,;-4.32,.16,;-2.86,-.32,;-2.46,-1.8,;-3.55,-2.89,;-3.15,-4.38,;-1.66,-4.78,;-1.27,-6.27,;-.57,-3.69,;-.97,-2.2,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525485 (US11174245, # I-135) Show SMILES Cn1cc(cn1)-c1cc(cc(F)n1)C(=O)\N=c1/[nH]c2cc(CN3CCOCC3)ccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:32.36,35.40,(7.08,-4.73,;7.08,-3.19,;5.83,-2.28,;6.31,-.82,;7.85,-.82,;8.33,-2.28,;5.54,.52,;4,.52,;3.23,1.85,;4,3.19,;5.54,3.19,;6.31,4.52,;6.31,1.85,;1.69,1.85,;.92,3.19,;.92,.52,;-.62,.52,;-1.53,1.76,;-2.99,1.29,;-4.32,2.06,;-5.66,1.29,;-6.99,2.06,;-6.99,3.6,;-5.66,4.37,;-5.66,5.91,;-6.99,6.68,;-8.33,5.91,;-8.33,4.37,;-5.66,-.25,;-4.32,-1.02,;-2.99,-.25,;-1.53,-.73,;-1.13,-2.22,;-2.22,-3.3,;-1.82,-4.79,;-.33,-5.19,;.07,-6.68,;.76,-4.1,;.36,-2.61,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525486 (US11174245, # I-136 | US11174245, # I-138) Show SMILES Cn1cc(cn1)-c1cc(cc(n1)C#N)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:26.29,29.33,(5.75,-4.31,;5.75,-2.77,;4.5,-1.87,;4.98,-.4,;6.52,-.4,;6.99,-1.87,;4.21,.93,;2.67,.93,;1.9,2.26,;2.67,3.6,;4.21,3.6,;4.98,2.26,;4.98,4.93,;5.75,6.27,;.36,2.26,;-.41,3.6,;-.41,.93,;-1.95,.93,;-2.86,2.18,;-4.32,1.7,;-5.66,2.47,;-6.99,1.7,;-6.99,.16,;-5.66,-.61,;-4.32,.16,;-2.86,-.32,;-2.46,-1.8,;-3.55,-2.89,;-3.15,-4.38,;-1.66,-4.78,;-1.27,-6.27,;-.57,-3.69,;-.97,-2.2,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525432 (US11174245, # I-015) Show SMILES Cn1cc(cn1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1C1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525481 (US11174245, # I-119) Show SMILES COc1ccccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@H]1CCC[C@H](O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525524 (US11174245, # I-202) Show SMILES CC(=O)N1CCC(CC1)c1ccc2n([C@@H]3CC[C@H](O)CC3)\c(=N\C(=O)c3cc(nc(c3)-c3cnn(C)c3)C#N)[nH]c2c1 |r,wU:14.14,17.18,(-10.33,3.98,;-8.99,4.75,;-8.99,6.29,;-7.66,3.98,;-6.32,4.75,;-4.99,3.98,;-4.99,2.44,;-6.32,1.67,;-7.66,2.44,;-3.66,1.67,;-3.66,.13,;-2.32,-.64,;-.99,.13,;.47,-.34,;.87,-1.83,;-.22,-2.92,;.18,-4.41,;1.67,-4.81,;2.07,-6.29,;2.76,-3.72,;2.36,-2.23,;1.38,.9,;2.92,.9,;3.69,2.24,;2.92,3.57,;5.23,2.24,;6,3.57,;7.54,3.57,;8.31,2.24,;7.54,.9,;6,.9,;8.31,-.43,;9.85,-.43,;10.33,-1.9,;9.08,-2.8,;9.08,-4.34,;7.83,-1.9,;8.31,4.9,;9.08,6.24,;.47,2.15,;-.99,1.67,;-2.32,2.44,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525468 (US11174245, # I-102) Show SMILES CN(C)Cc1cccc(c1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1CC(C)(C)O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525525 (US11174245, # I-203) Show SMILES Cn1ncc(c1Cl)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:25.28,28.32,(5.75,-2.98,;5.75,-1.44,;6.99,-.53,;6.52,.93,;4.98,.93,;4.5,-.53,;3.17,-1.3,;4.21,2.26,;2.67,2.26,;1.9,3.6,;2.67,4.93,;4.21,4.93,;4.98,3.6,;.36,3.6,;-.41,4.93,;-.41,2.26,;-1.95,2.26,;-2.86,3.51,;-4.32,3.03,;-5.66,3.8,;-6.99,3.03,;-6.99,1.49,;-5.66,.72,;-4.32,1.49,;-2.86,1.02,;-2.46,-.47,;-3.55,-1.56,;-3.15,-3.05,;-1.66,-3.44,;-1.27,-4.93,;-.57,-2.36,;-.97,-.87,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525523 (US11174245, # I-201) Show SMILES O[C@H]1CC[C@H](CC1)n1c2ccccc2[nH]\c1=N/C(=O)c1ccnc(c1)-c1cnn(c1)C(F)F |r,wU:4.7,1.0,(-2.55,-4.93,;-2.95,-3.44,;-4.44,-3.05,;-4.84,-1.56,;-3.75,-.47,;-2.26,-.87,;-1.86,-2.36,;-4.15,1.02,;-5.61,1.49,;-6.95,.72,;-8.28,1.49,;-8.28,3.03,;-6.95,3.8,;-5.61,3.03,;-4.15,3.51,;-3.24,2.26,;-1.7,2.26,;-.93,3.6,;-1.7,4.93,;.61,3.6,;1.38,4.93,;2.92,4.93,;3.69,3.6,;2.92,2.26,;1.38,2.26,;3.69,.93,;3.21,-.53,;4.46,-1.44,;5.7,-.53,;5.23,.93,;7.19,-.93,;8.28,.16,;7.59,-2.42,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525516 (US11174245, # I-189) Show SMILES COc1ccccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2cc(ccc2n1CC(C)(C)O)C1CCCN(C1)C(C)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525425 (US11174245, # I-008) Show SMILES CC(=O)N1CCC(CC1)c1ccc2n(C3CCCC3)\c(=N\C(=O)c3ccnc(c3)-c3cnn(C)c3)[nH]c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525499 (US11174245, # I-158) Show SMILES COc1ccccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2cc(ccc2n1CC(C)(C)O)C1CCN(C1)C(C)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525451 (US11174245, # I-036) Show SMILES Cn1cc(cn1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@H]1CC[C@H](O)CC1 |r,wU:24.27,wD:27.31,(5.75,-2.98,;5.75,-1.44,;4.5,-.53,;4.98,.93,;6.52,.93,;6.99,-.53,;4.21,2.26,;2.67,2.26,;1.9,3.6,;2.67,4.93,;4.21,4.93,;4.98,3.6,;.36,3.6,;-.41,4.93,;-.41,2.26,;-1.95,2.26,;-2.86,3.51,;-4.32,3.03,;-5.66,3.8,;-6.99,3.03,;-6.99,1.49,;-5.66,.72,;-4.32,1.49,;-2.86,1.02,;-2.46,-.47,;-.97,-.87,;-.57,-2.36,;-1.66,-3.44,;-1.27,-4.93,;-3.15,-3.05,;-3.55,-1.56,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525512 (US11174245, # I-181) Show SMILES COc1ccccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2cc(CN3CCOCC3)ccc2n1[C@H]1CCC[C@H](O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525492 (US11174245, # I-145) Show SMILES Cn1cc(cn1)-c1cc(cc(n1)C#N)C(=O)\N=c1/[nH]c2cc(CN3CCOCC3)ccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:33.37,36.41,(8.41,-4.31,;8.41,-2.77,;7.17,-1.87,;7.64,-.4,;9.18,-.4,;9.66,-1.87,;6.87,.93,;5.33,.93,;4.56,2.26,;5.33,3.6,;6.87,3.6,;7.64,2.26,;7.64,4.93,;8.41,6.27,;3.02,2.26,;2.25,3.6,;2.25,.93,;.71,.93,;-.19,2.18,;-1.66,1.7,;-2.99,2.47,;-4.32,1.7,;-5.66,2.47,;-6.99,1.7,;-8.33,2.47,;-9.66,1.7,;-9.66,.16,;-8.33,-.61,;-6.99,.16,;-4.32,.16,;-2.99,-.61,;-1.66,.16,;-.19,-.32,;.21,-1.8,;-.88,-2.89,;-.48,-4.38,;1,-4.78,;1.4,-6.27,;2.09,-3.69,;1.69,-2.2,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525545 (US11174245, # I-223) Show SMILES Cc1cc(cc(n1)-c1cnn(C)c1)C(=O)\N=c1/[nH]c2ccc(CN3CCOCC3)cc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:32.36,35.40,(4.17,6.41,;4.17,4.87,;2.83,4.1,;2.83,2.56,;4.17,1.79,;5.5,2.56,;5.5,4.1,;6.83,1.79,;8.3,2.26,;9.2,1.02,;8.3,-.23,;9.07,-1.56,;6.83,.25,;1.5,1.79,;.16,2.56,;1.5,.25,;.16,-.52,;-1.24,.11,;-2.27,-1.04,;-3.81,-1.04,;-4.58,-2.37,;-3.81,-3.71,;-4.58,-5.04,;-6.12,-5.04,;-6.89,-3.71,;-8.43,-3.71,;-9.2,-5.04,;-8.43,-6.37,;-6.89,-6.37,;-2.27,-3.71,;-1.5,-2.37,;0,-2.05,;1.09,-3.14,;.69,-4.63,;1.78,-5.72,;3.27,-5.32,;4.36,-6.41,;3.67,-3.83,;2.58,-2.74,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525470 (US11174245, # I-107) Show SMILES O[C@H]1CC[C@H](CC1)n1c2ccccc2[nH]\c1=N/C(=O)c1ccnc(c1)-c1ccccc1 |r,wU:4.7,1.0,(-1.41,-4.93,;-1.81,-3.44,;-3.3,-3.05,;-3.7,-1.56,;-2.61,-.47,;-1.12,-.87,;-.72,-2.36,;-3.01,1.02,;-4.47,1.49,;-5.8,.72,;-7.14,1.49,;-7.14,3.03,;-5.8,3.8,;-4.47,3.03,;-3.01,3.51,;-2.1,2.26,;-.56,2.26,;.21,3.6,;-.56,4.93,;1.75,3.6,;2.52,4.93,;4.06,4.93,;4.83,3.6,;4.06,2.26,;2.52,2.26,;4.83,.93,;4.06,-.4,;4.83,-1.74,;6.37,-1.74,;7.14,-.4,;6.37,.93,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525429 (US11174245, # I-012) Show SMILES CC(C)Cn1c2ccccc2[nH]\c1=N/C(=O)c1ccnc(c1)-c1cnn(C)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525490 (US11174245, # I-143) Show SMILES Cc1cc(cc(n1)-c1cnn(C)c1)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:25.28,28.32,(4.98,5.6,;4.21,4.26,;2.67,4.26,;1.9,2.93,;2.67,1.6,;4.21,1.6,;4.98,2.93,;4.98,.26,;6.52,.26,;6.99,-1.2,;5.75,-2.11,;5.75,-3.65,;4.5,-1.2,;.36,2.93,;-.41,4.26,;-.41,1.6,;-1.95,1.6,;-2.86,2.84,;-4.32,2.37,;-5.66,3.14,;-6.99,2.37,;-6.99,.83,;-5.66,.06,;-4.32,.83,;-2.86,.35,;-2.46,-1.14,;-3.55,-2.22,;-3.15,-3.71,;-1.66,-4.11,;-1.27,-5.6,;-.57,-3.02,;-.97,-1.53,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525489 (US11174245, # I-141) Show SMILES O[C@H]1CC[C@H](CC1)n1c2ccccc2[nH]\c1=N/C(=O)c1ccnc(c1)-c1ccccc1F |r,wU:4.7,1.0,(-1.41,-4.93,;-1.81,-3.44,;-3.3,-3.05,;-3.7,-1.56,;-2.61,-.47,;-1.12,-.87,;-.72,-2.36,;-3.01,1.02,;-4.47,1.49,;-5.8,.72,;-7.14,1.49,;-7.14,3.03,;-5.8,3.8,;-4.47,3.03,;-3.01,3.51,;-2.1,2.26,;-.56,2.26,;.21,3.6,;-.56,4.93,;1.75,3.6,;2.52,4.93,;4.06,4.93,;4.83,3.6,;4.06,2.26,;2.52,2.26,;4.83,.93,;4.06,-.4,;4.83,-1.74,;6.37,-1.74,;7.14,-.4,;6.37,.93,;7.14,2.26,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525543 (US11174245, # I-221) Show SMILES Cc1cc(cc(n1)-c1cnn(C)c1)C(=O)\N=c1/[nH]c2ccc(CN3CCOCC3)cc2n1C1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525522 (US11174245, # I-200) Show SMILES O[C@H]1CC[C@H](CC1)n1c2ccccc2[nH]\c1=N/C(=O)c1ccnc(c1)-c1cnn2CC(F)(F)COc12 |r,wU:4.7,1.0,(-1.27,-4.93,;-1.66,-3.44,;-3.15,-3.05,;-3.55,-1.56,;-2.46,-.47,;-.97,-.87,;-.57,-2.36,;-2.86,1.02,;-4.32,1.49,;-5.66,.72,;-6.99,1.49,;-6.99,3.03,;-5.66,3.8,;-4.32,3.03,;-2.86,3.51,;-1.95,2.26,;-.41,2.26,;.36,3.6,;-.41,4.93,;1.9,3.6,;2.67,4.93,;4.21,4.93,;4.98,3.6,;4.21,2.26,;2.67,2.26,;4.98,.93,;6.52,.93,;6.99,-.53,;5.75,-1.44,;5.58,-2.97,;4.18,-3.6,;3.41,-4.93,;4.95,-4.93,;2.93,-2.69,;3.09,-1.16,;4.5,-.53,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525500 (US11174245, # I-161) Show SMILES Cc1cccc(c1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:25.28,28.32,(4.06,-3.07,;4.83,-1.74,;6.37,-1.74,;7.14,-.4,;6.37,.93,;4.83,.93,;4.06,-.4,;4.06,2.26,;2.52,2.26,;1.75,3.6,;2.52,4.93,;4.06,4.93,;4.83,3.6,;.21,3.6,;-.56,4.93,;-.56,2.26,;-2.1,2.26,;-3.01,3.51,;-4.47,3.03,;-5.8,3.8,;-7.14,3.03,;-7.14,1.49,;-5.8,.72,;-4.47,1.49,;-3.01,1.02,;-2.61,-.47,;-3.7,-1.56,;-3.3,-3.05,;-1.81,-3.44,;-1.41,-4.93,;-.72,-2.36,;-1.12,-.87,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525535 (US11174245, # I-212) Show SMILES Cn1cc(cn1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1C1CCCS(=O)(=O)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525519 (US11174245, # I-197) Show SMILES Cc1cc(cc(n1)-c1cnn(C)c1)C(=O)\N=c1/[nH]c2cc(CN3CCOCC3)ccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:32.36,35.40,(6.31,4.52,;5.54,3.19,;4,3.19,;3.23,1.85,;4,.52,;5.54,.52,;6.31,1.85,;6.31,-.82,;7.85,-.82,;8.33,-2.28,;7.08,-3.19,;7.08,-4.73,;5.83,-2.28,;1.69,1.85,;.92,3.19,;.92,.52,;-.62,.52,;-1.53,1.76,;-2.99,1.29,;-4.32,2.06,;-5.66,1.29,;-6.99,2.06,;-6.99,3.6,;-5.66,4.37,;-5.66,5.91,;-6.99,6.68,;-8.33,5.91,;-8.33,4.37,;-5.66,-.25,;-4.32,-1.02,;-2.99,-.25,;-1.53,-.73,;-1.13,-2.22,;-2.22,-3.3,;-1.82,-4.79,;-.33,-5.19,;.07,-6.68,;.76,-4.1,;.36,-2.61,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525494 (US11174245, # I-146) Show SMILES Cn1cc(cn1)-c1cc(cc(Cl)n1)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:25.28,28.32,(7.66,-1.97,;6.32,-1.2,;5.85,.26,;4.31,.26,;3.83,-1.2,;5.08,-2.11,;3.54,1.6,;2,1.6,;1.23,2.93,;2,4.26,;3.54,4.26,;4.31,5.6,;4.31,2.93,;-.31,2.93,;-1.08,4.26,;-1.08,1.6,;-2.62,1.6,;-3.53,2.84,;-4.99,2.37,;-6.32,3.14,;-7.66,2.37,;-7.66,.83,;-6.32,.06,;-4.99,.83,;-3.53,.35,;-3.13,-1.14,;-4.22,-2.22,;-3.82,-3.71,;-2.33,-4.11,;-1.93,-5.6,;-1.24,-3.02,;-1.64,-1.53,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525505 (US11174245, # I-169) Show SMILES COc1cc(F)ccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:27.30,30.34,(6.37,3.6,;7.14,2.26,;6.37,.93,;7.14,-.4,;6.37,-1.74,;7.14,-3.07,;4.83,-1.74,;4.06,-.4,;4.83,.93,;4.06,2.26,;2.52,2.26,;1.75,3.6,;2.52,4.93,;4.06,4.93,;4.83,3.6,;.21,3.6,;-.56,4.93,;-.56,2.26,;-2.1,2.26,;-3.01,3.51,;-4.47,3.03,;-5.8,3.8,;-7.14,3.03,;-7.14,1.49,;-5.8,.72,;-4.47,1.49,;-3.01,1.02,;-2.61,-.47,;-3.7,-1.56,;-3.3,-3.05,;-1.81,-3.44,;-1.41,-4.93,;-.72,-2.36,;-1.12,-.87,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525447 (US11174245, # I-032) Show SMILES CN1CCC(CC1)c1ccc2n(CC(C)(C)O)\c(=N\C(=O)c3ccnc(c3)-c3cnn4cccnc34)[nH]c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525446 (US11174245, # I-031) Show SMILES COc1ccncc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2cc(ccc2n1CC(C)(C)O)C1CCN(CC1)C(C)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525530 (US11174245, # I-207) Show SMILES Cn1cc(cn1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@@H]1C[C@@H](O)C[C@@H](O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525518 (US11174245, # I-196) Show SMILES COc1ccncc1-c1cc(cc(n1)C#N)C(=O)\N=c1/[nH]c2cc(CN3CCOCC3)ccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:35.39,38.43,(9.24,.52,;7.7,.52,;6.93,-.82,;7.7,-2.15,;6.93,-3.48,;5.39,-3.48,;4.62,-2.15,;5.39,-.82,;4.62,.52,;3.08,.52,;2.31,1.85,;3.08,3.19,;4.62,3.19,;5.39,1.85,;5.39,4.52,;6.16,5.85,;.77,1.85,;0,3.19,;0,.52,;-1.54,.52,;-2.44,1.76,;-3.91,1.29,;-5.24,2.06,;-6.57,1.29,;-7.91,2.06,;-7.91,3.6,;-6.57,4.37,;-6.57,5.91,;-7.91,6.68,;-9.24,5.91,;-9.24,4.37,;-6.57,-.25,;-5.24,-1.02,;-3.91,-.25,;-2.44,-.73,;-2.04,-2.22,;-3.13,-3.3,;-2.73,-4.79,;-1.25,-5.19,;-.85,-6.68,;-.16,-4.1,;-.56,-2.61,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525475 (US11174245, # I-112 | US11174245, # I-126) Show SMILES Cn1cc(cn1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@H]1CCC[C@@H](O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525475 (US11174245, # I-112 | US11174245, # I-126) Show SMILES Cn1cc(cn1)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1[C@H]1CCC[C@@H](O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525495 (US11174245, # I-148) Show SMILES COc1ccccc1-c1cc(ccn1)C(=O)\N=c1/[nH]c2cc(CN3CCOCC3)ccc2n1[C@H]1CCC[C@@H](O)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525528 (US11174245, # I-205) Show SMILES CC(=O)N1CCC(CC1)c1ccc2n([C@@H]3CC[C@H](O)CC3)\c(=N\C(=O)c3cc(C)nc(c3)-c3cnn(C)c3)[nH]c2c1 |r,wU:14.14,17.18,(-10.33,3.98,;-8.99,4.75,;-8.99,6.29,;-7.66,3.98,;-6.32,4.75,;-4.99,3.98,;-4.99,2.44,;-6.32,1.67,;-7.66,2.44,;-3.66,1.67,;-3.66,.13,;-2.32,-.64,;-.99,.13,;.47,-.34,;.87,-1.83,;-.22,-2.92,;.18,-4.41,;1.67,-4.81,;2.07,-6.29,;2.76,-3.72,;2.36,-2.23,;1.38,.9,;2.92,.9,;3.69,2.24,;2.92,3.57,;5.23,2.24,;6,3.57,;7.54,3.57,;8.31,4.9,;8.31,2.24,;7.54,.9,;6,.9,;8.31,-.43,;9.85,-.43,;10.33,-1.9,;9.08,-2.8,;9.08,-4.34,;7.83,-1.9,;.47,2.15,;-.99,1.67,;-2.32,2.44,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525473 (US11174245, # I-110) Show SMILES Cc1ccc2n([C@@H]3CC[C@H](O)CC3)\c(=N\C(=O)c3ccnc(c3)-c3cnn4cccnc34)[nH]c2c1 |r,wU:6.5,9.9,(-7.66,3.8,;-6.32,3.03,;-6.32,1.49,;-4.99,.72,;-3.66,1.49,;-2.19,1.02,;-1.79,-.47,;-2.88,-1.56,;-2.48,-3.05,;-1,-3.44,;-.6,-4.93,;.09,-2.36,;-.31,-.87,;-1.29,2.26,;.25,2.26,;1.02,3.6,;.25,4.93,;2.56,3.6,;3.33,4.93,;4.87,4.93,;5.64,3.6,;4.87,2.26,;3.33,2.26,;5.64,.93,;7.18,.93,;7.66,-.53,;6.41,-1.44,;6.25,-2.97,;4.84,-3.6,;3.6,-2.69,;3.76,-1.16,;5.17,-.53,;-2.19,3.51,;-3.66,3.03,;-4.99,3.8,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [695-1022,T790M,C797S,L858R] (Homo sapiens (Human))	BDBM525433 (US11174245, # I-017) Show SMILES Cc1c(cnn1C)-c1cc(ccn1)C(=O)\N=c1/[nH]c2ccccc2n1CC(C)(C)O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair

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